Palestinians carry away the body of a man killed in Israeli bombardment from the morgue of the Al-Shifa hospital in Gaza City on March 15, 2024. (PHOTO / AFP)

GAZA/JERUSALEM - At least 250 Palestinians were killed and injured due to an Israeli raid on the Shifa Medical Complex, the largest hospital in Gaza City, the Hamas-run media office said on Tuesday.

It said in a statement that the Israeli troops fired bullets, shells, and missiles intensively toward patients, displaced persons, and civilians during their raid, resulting in the injury and death of more than 250 Palestinians, with some facilities inside the hospital being burned.

The statement did not specify the exact number of the death toll in the raid.

The statement added that the raid involved hundreds of Israeli soldiers armed with weapons, police dogs, dozens of tanks, drones, and helicopters.

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The office held Israel and the United States fully responsible for what it termed a "massacre", calling on international and UN organizations to "intervene immediately to stop the aggression on Gaza, which targets civilians, children, and women".

The Israel Defense Forces said "precise operations" were launched targeting the hospital, and it had killed over 50 Hamas militants and apprehended almost 180 others

In a separate statement, Hamas said "the attempt to use the escalation of barbaric aggression against civilians as a means of pressure and extortion to achieve their goals will not succeed".

The Israeli army on Monday launched an operation within the complex, marking its second raid on the hospital since the onset of the Israel-Hamas conflict on October 7 last year. The first raid occurred in November last year. 

READ MORE: Israel army seizes Al-Shifa Hospital, Gaza toll at 31,726

Israeli army's spokesman Avichay Adraee said in a statement on social media platform X that the Israeli army and the General Security Service Shin Bet continued their operations in the Shifa complex for the second consecutive day.

Palestinians carry their belongings after visiting their houses destroyed in the Israeli offensive on Khan Younis, Gaza Strip, March 6, 2024. (PHOTO / AP)

He added that the Israeli forces were "eliminating saboteurs in face-to-face battles" and had uncovered combat equipment in the area while avoiding harm to civilians, patients, medical personnel, and medical facilities.

The Israel Defense Forces said "precise operations" were launched targeting the hospital, and it had killed over 50 Hamas militants and apprehended almost 180 others.

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Hamas militants were killed in close-quarters combat, and the Israeli army located weapons in the area "while avoiding harm to civilians, medical staff, and medical equipment", the forces said.

In the area of Al-Qarara in Khan Younis, the Israeli army killed Palestinian militants and destroyed infrastructure, including one from which anti-tank missiles were launched at Israeli troops two days ago, the forces added.

Also on Tuesday, the IDF announced the death of a commander. The death of the 51-year-old commander brought the death toll of the Israeli army since the beginning of the Israel-Hamas conflict to 594.