A SpaceX Falcon 9 rocket with the Crew Dragon capsule lifts off from Launch Pad 39A at the Kennedy Space Center in Cape Canaveral, Florida, Nov 10, 2021. (CHRIS O'MEARA / AP PHOTO)

NEW YORK - The US National Aeronautics and Space Administration and private player SpaceX successfully launched Crew-3 mission into orbit on Wednesday night following delays due to unfavorable weather conditions and medical conditions with one of the crew members, according to NASA.

SpaceX's Crew Dragon Endurance spacecraft has successfully separated from the Falcon 9 rocket's second stage and is now flying on its own, according to a release by NASA.

The spacecraft and SpaceX Falcon 9 rocket lifted off at 9:03 pm EST (0203 GMT on Thursday) from Launch Complex 39A at the agency's Kennedy Space Center in Florida

The spacecraft and SpaceX Falcon 9 rocket lifted off at 9:03 pm EST (0203 GMT on Thursday) from Launch Complex 39A at the agency's Kennedy Space Center in Florida.

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The spacecraft has safely reached orbit, and its nose cone has been opened, added NASA.

The crew members include NASA astronauts Raja Chari, mission commander; Tom Marshburn, pilot; and Kayla Barron, mission specialist; as well as European Space Agency astronaut Matthias Maurer.

They are expected to arrive at the International Space Station about 22 hours later at around 7:10 pm EST on Nov 11 (0010 GMT on Nov. 12), according to NASA.

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Crew-3 astronauts are scheduled for a long-duration science mission aboard the orbiting laboratory, living and working as part of what is expected to be a seven-member crew, according to NASA.

Four astronauts with the SpaceX Crew-2 mission returned to earth on Monday night.